A trial published in Nutritional Psychiatry put urinary kryptopyrrole testing under controlled clinical scrutiny, examining whether this proposed biomarker meaningfully tracks symptoms of generalised anxiety.1 Their findings challenge its clinical validity:...

Structured consumption of fresh apples may offer a surprisingly practical approach to birch pollen food allergy syndrome (PFAS). Mueller and colleagues report that gradually increasing apple exposure produced substantial and sustained tolerance, accompanied by...

Iodine deficiency remains a concern during pregnancy, even in countries with established iodised salt programmes. A study in the British Journal of Nutrition suggests that iodine supplementation and dietary intake are important determinants of maternal iodine status,...

High-dose vitamin B6 supplementation may significantly reduce depressive symptoms, according to a new randomised controlled study. The findings suggest that vitamin B6 could offer a low-cost nutritional intervention for depression, although questions remain about...

A new case–control study strengthens the emerging link between thiamine (vitamin B1) deficiency and chronic migraine. When considered alongside recent intervention studies, the findings suggest that nutritional status may represent an overlooked, modifiable factor in...

In a new review in the journal Nutrients investigators examine how common single nucleotide polymorphisms (SNPs) may influence cardiovascular risk and dietary responses. They identify plausible applications in personalised nutrition and conclude that genetic testing...

New nutrigenomic evidence links folate metabolism with premenstrual depression. Zeitoun and colleagues1 report that the common MTHFR C677T variant was associated with higher odds of premenstrual depressive symptoms—but only among women with lower habitual folate...

Few molecules have acquired quite the aura of NAD⁺. In longevity clinics, supplement aisles and online forums, it is often presented as cellular fuel with the potential to restore youthful energy, sharpen metabolism and perhaps slow ageing itself. A new systematic...

Fibromyalgia has long been one of medicine’s most frustrating puzzles: widespread pain, poor sleep, fatigue, “fibro fog,” and often a trail of digestive or allergy-like symptoms—yet no single test that explains it all. A new narrative review asks whether, for a subset...

Saffron is already one of the world’s most coveted spices: delicate red threads with a price to match, prized in cooking for colour, aroma and a slightly honeyed bitterness. It has also, increasingly, become a serious subject for mental-health researchers. A new...

For most people living with chronic migraine, glucose metabolism and diet are not part of the conversation in clinical management. Yet a new study suggests that metabolic asessment is important and may point towards biological features that could help personalise...

Glucosamine, the familiar joint-health supplement, has become an unexpected focus of Alzheimer’s research. A new Nature Metabolism paper suggests that in brains already affected by Alzheimer’s-like disease, glucosamine may feed an abnormal metabolic process and worsen...

What if food science has been asking too small a question? For more than a century, nutrition has largely treated food as a ledger of calories, proteins, fats, vitamins and minerals. That approach has saved lives and remains indispensable. But a provocative new...

Menopause is often discussed as a list of familiar complaints: poor sleep, low mood, brain fog, fatigue, changing weight and, later, worries about bone health. But a new case report in the Journal of the American Nutrition Association argues that the more useful...

Modern breast cancer medicine has become remarkably good at confronting the tumour itself. Diagnosis is sharper, surgery more precise, drugs more targeted and survival rates higher. Yet for many women, the treatment journey still leaves a conspicuous gap: who is...